32 research outputs found
UAS Literary & Arts Journal
Proof copy provided by Tidal Echoes.Tidal Echoes is an annual showcase of writers and artists with one thing in common: a life surrounded by the rainforests and waterways of Southeast Alaska.Davy Josh’s Note -- A Note from Chalise -- A Note from Emily Wall -- Brain Bucket -- Cephalic index -- A Gift of Fat for the Fire -- Our heroes have always been... -- Colorful Clouds -- Role Model -- Anchors -- Out My Window -- Adaptation -- Bookshelves -- In the Flow -- It’s a Small World Parade Float -- Sexy -- Death by Algebra -- Friend -- mirabile visu -- Exchange II -- F A D E -- Borne Alone -- Continuum -- The Week Before St. Valentine’s -- Bottled Up -- Untitled -- Early Morning Conspiracy Theory -- Westport -- Boulder Creek -- Jumping Off Rooftops -- Staying in the Room With Ernestine Hayes -- Blueberry -- After Neruda By Way of Bly (Tenure) -- Magic of Water -- Old Tom Steals the Light -- Old Tom Finds a Whale -- Research Project -- Guppy (boat) -- Arizona Spyder -- From Anthropomorphism to Zoomorphism -- Bus Stop -- December 1, 1955 -- Between Tides at Twilight -- Dementia -- Winter Ferry -- Coming into Auke Bay -- The Search for Jane Rogers -- Inlaid Tea Cups -- The Big Melt -- Kingsmill Reef -- Despite Man’s Best Efforts to Ruin It -- Roberts from Flume -- India Scarf -- Painted and Petrified -- Medicine Bag -- Merrill Field -- Deadly Kites -- Brazilian Ghetto -- Seattle Riff -- The Gospel Truth of My Gay Bird -- Signing the Divorce Papers -- Red Shades -- Holey Cow -- Untitled -- Series of Cedar Baskets -- A Conversation With Ranunculus -- Deconstruction -- Sandy Beach -- Threshold -- Oil and Honesty: An Interview with Artist and Professor David Woodie -- Mitkof #3 -- Still Life -- First Day of Fall -- Falling in the Garden -- After Finishing an Activities Report for the Dean -- Homage to Po Chü-I -- Nunc Dimittis -- Do Wise Men Have Bad Days? -- To the Plain Land -- Flood of ‘69 -- How a woman makes her own wine -- Untitled (translation from Russian) -- Existential Sestina -- It’s the knowing -- Blood and Guts -- Sometime Walking on the Beach -- Untitled -- Connecting the Pieces -- Hemlock -- Klawock Island -- Driven By the Tides -- Lunch -- The People -- Howling Dog -- Winter Cabin Lullaby -- Chain Gang -- A Review of Social Groups in Female Homo Sapiens as Exemplified by Mammary Restraint -- Apparatuses -- Douglas Island Bridge -- Going Home -- Author and Artist Biographie
Consequences of Internet Use in College Students
The purposes of the research project were to explore how much time college students spend on the Internet and the consequences for college students who use the Internet
Alzheimer’s disease genetic risk and cognitive reserve in relationship to long-term cognitive trajectories among cognitively normal individuals
Background:
Both Alzheimer’s disease (AD) genetic risk factors and indices of cognitive reserve (CR) influence risk of cognitive decline, but it remains unclear whether they interact. This study examined whether a CR index score modifies the relationship between AD genetic risk factors and long-term cognitive trajectories in a large sample of individuals with normal cognition.
Methods:
Analyses used data from the Preclinical AD Consortium, including harmonized data from 5 longitudinal cohort studies. Participants were cognitively normal at baseline (M baseline age = 64 years, 59% female) and underwent 10 years of follow-up, on average. AD genetic risk was measured by (i) apolipoprotein-E (APOE) genetic status (APOE-ε2 and APOE-ε4 vs. APOE-ε3; N = 1819) and (ii) AD polygenic risk scores (AD-PRS; N = 1175). A CR index was calculated by combining years of education and literacy scores. Longitudinal cognitive performance was measured by harmonized factor scores for global cognition, episodic memory, and executive function.
Results:
In mixed-effects models, higher CR index scores were associated with better baseline cognitive performance for all cognitive outcomes. APOE-ε4 genotype and AD-PRS that included the APOE region (AD-PRSAPOE) were associated with declines in all cognitive domains, whereas AD-PRS that excluded the APOE region (AD-PRSw/oAPOE) was associated with declines in executive function and global cognition, but not memory. There were significant 3-way CR index score × APOE-ε4 × time interactions for the global (p = 0.04, effect size = 0.16) and memory scores (p = 0.01, effect size = 0.22), indicating the negative effect of APOE-ε4 genotype on global and episodic memory score change was attenuated among individuals with higher CR index scores. In contrast, levels of CR did not attenuate APOE-ε4-related declines in executive function or declines associated with higher AD-PRS. APOE-ε2 genotype was unrelated to cognition.
Conclusions:
These results suggest that APOE-ε4 and non-APOE-ε4 AD polygenic risk are independently associated with global cognitive and executive function declines among individuals with normal cognition at baseline, but only APOE-ε4 is associated with declines in episodic memory. Importantly, higher levels of CR may mitigate APOE-ε4-related declines in some cognitive domains. Future research is needed to address study limitations, including generalizability due to cohort demographic characteristics
UAS Literary & Arts Journal
Proof copy provided by Tidal Echoes.Tidal Echoes presents an annual showcase of writers and artists who share one thing in common: a life surrounded by the rainforests and waterways of Southeast Alaska.A Note from Chalise Fisk -- A Note from Kaleigh Lambert -- A Note from Emily Wall -- A Note from Katie Spielberger -- The Sacred and the Profane -- Wild Polaroid -- Reflecting on the Old Dock on Auke Lake -- Dating Myself Forwarding John Updike's "Baseball" on The Writer's Almanac, June 22, 2009 -- Thoughts after Working on Salmon Eggs from our Grandson -- Burnt the Tea -- I Was in Love with a Boy Who Loved Dog-Sledding -- The Last Word -- Salmon Woman -- Organ Donor -- At First Sight -- The Dichotomy of Dog Salmon -- Winter in Lingit Aani Brings Magpies and Ravens -- To My Father, After My Last Summer Crewing on the Katrina Louise -- Damp -- Art 105 -- Portrait of a Man -- An Interview with Jane Terzis, Featured Artist -- I Have the Capacity for Patience -- 4-H -- Wildthing at the Glacier -- I Have the Capacity for Honesty -- I Have the Capacity for Obsessive Neatness -- I Have the Capacity for Stubbornness -- I Have the Capacity for Meanness -- I Have the Capacity to Kill -- Zora’s -- Thursdays after dinner -- Nixon’s reelection day -- They Break Not His Legs -- The girl -- How a mother remembers -- Atonement -- Earthbound -- Romance in the Newsprint (strangely devised personal ads) -- Memories of Winter -- Metamorphosis -- Rivers in Washington -- Light at the End of the Tunnel -- Sisters’ Islands -- Distress Signal -- Ice Caves and a Warm Wind -- Coke Train -- My Backyard’s Winter Anatomy -- Sunny With Chance of Feathers | Milky Way -- Tag -- Islands -- Such Great Heights -- The Seaweed Holt -- Sockeye -- Insider/Outsider | Little Bitch -- Pinocchio | Taylor, Home Depot, Tampa, 2001 -- Danielle and Zouzou -- My Father | Nine-Year-Old Kid -- A Little Bit of Everything: Interview with Nick Jans, Featured Writer -- Crossing Sawyer -- Summer’s Drift -- Waterline -- Ghost Meat, from the novel in process Nakolik -- The Giant’s Hand -- Rain Country -- The Stone Kyrielle -- Autograph -- Shards -- In Her Yellow Docs, She Shines -- Claudius Maximus -- Tracing Constellations -- Chasing the Promised Land -- My Favorite Story About Elizabeth -- The Destruction of the Russian Fort at New Archangel -- Jack of Hearts -- Beached -- Autumn Reflection -- JoJo | Guardian | King of the Jungle -- Child in the Woods -- Respite -- Burial at Sea -- Gold -- Geared for Drinking -- First Contact -- Fish Story -- Winter Mornings -- Downpour -- Feather -- Snowbirds -- The Sushi Chef Takes his Break During a Snowstorm on Lincoln Street -- Author and Artist Biographies -- Wash Day in Cobh, Ireland -- Alaska Fisherman’s Building -- Bleed -- Auke Lake Tre